Hypothalamic-pituitary-adrenal axis function in ankylosing spondylitis
نویسندگان
چکیده
منابع مشابه
Hypothalamic-pituitary-adrenal axis function in ankylosing spondylitis.
OBJECTIVE To assess basal function and responsiveness of the hypothalamic-pituitary-adrenal (HPA) axis in patients with ankylosing spondylitis during dynamic testing. METHODS Insulin induced hypoglycaemia (IIH) (Actrapid HM 0.1 IU/kg, as intravenous bolus) was induced in 17 patients and 11 healthy controls matched for age, sex, and body mass index. Concentrations of glucose, adrenocorticotrop...
متن کاملHypothalamic-pituitary-adrenal axis in patients with ankylosing spondylitis.
OBJECTIVE To investigate the hypothalamic-pituitary-adrenal (HPA) axis via the insulin-tolerance test (ITT), standard-dose (250 microg) ACTH test (SDT) and low-dose (1 microg) ACTH test (LDT) in patients with ankylosing spondylitis (AS). DESIGN The study group included 13 male patients with AS who were diagnosed according to the Modified New York criteria, and 8 healthy male subjects and was ...
متن کاملHypothalamic-Pituitary-Adrenal Axis Function in Chronic Fatigue Syndrome
There is evidence for a hypofunction of the hypothalamicpituitary-adrenal (HPA) axis in a proportion of the patients with chronic fatigue syndrome (CFS), despite the negative studies and methodological difficulties. In this review, we focus on challenge studies and on the role of the HPA axis in the pathogenesis of CFS. Mild hypocortisolism, blunted adrenocorticotropin response to stressors and...
متن کاملHypothalamic-pituitary-adrenal axis function in patients with bipolar disorder.
BACKGROUND Hypothalamic-pituitary-adrenal (HPA) axis function, as variously measured by the responses to the combined dexamethasone/corticotrophin-releasing hormone (dex/CRH) test, the dexamethasone suppression test (DST) and basal cortisol levels, has been reported to be abnormal in bipolar disorder. AIMS To test the hypothesis that HPA axis dysfunction persists in patients in remission from...
متن کاملHypothalamic-pituitary-adrenal function.
Basal hypothalamic-pituitary-adrenal (HPA) function is characterised by pulses of corticosterone secretion followed by a transient refractory period when the axis appears to be inhibited. In females pulses of corticosterone secretion occur approximately once per hour with variation in pulse amplitude underlying a diurnal rhythm. Males show smaller pulses of secretion which become widely spaced ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2004
ISSN: 0003-4967
DOI: 10.1136/ard.2003.006940